The Xtra Scoop
Equine Protozoal Myeloencephalitis (EPM) - (Opossum Disease)
EPM mimics many other neurological conditions.  However, the
neurological symptoms associated with EPM can include the following:

  • Lameness or weakness
  • A lack of coordination and difficulty in moving
  • A loss of balance
  • Seizures

Accurate diagnosis of EPM is difficult because of the numerous similarities
to other neurological conditions.  The primary parasite that causes the
disease is a single-celled protozoan organism, Sarcocystis Neurona.
In addition, because of IFA (immunofluorescence assay) cross-reactivity,
blood tests by IFA have limited values for diagnosis.  A more accurate
alternative is the cerebrospinal fluid (CSF) western blot test.  However, it is
very expensive, and collecting a sample exposes the patient and the
veterinarian to unnecessary risks.


Current Therapies
The use of Karbo Combo has, in field studies, proven very effective in
resolving the symptoms of EPM.

Karbo Combo consists of encapsulated enzymes, vitamins, bacteria, and
large numbers of mannan, and glucan oligosaccharides.  In addition, the
formula also contains glycocomponents necessary for tying up and
neutralizing various toxins.

The objective of Karbo Combo is to attach and bind to the surface lectins of
pathogenic viruses, bacteria, protozoa, and toxins, therefore rendering them
incapable of colonization and reproduction. The stimulation and modulation
of the complex immune system by this formulation is not clearly understood
at this time.

Information provided by:
Gomer's Inc.
Equine Protozoal
Myeloencephalitis (EPM)
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These products are not intended to diagnose, treat, cure, or prevent any disease.